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NMQual version 7.0.1

Tuesday, 06 October 2009 11:43
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Metrum Institute announces the availability of NMQual version 7.0.1. NMQual 7 supports NONMEM 7 and is back-compatible with NONMEM 6. It has been tested with Intel Fortran and g95 compilers on both Macintosh and Windows operating systems.

The configuration template (config.template.xml) installs NONMEM 7 on a Windows computer using Intel Fortran; suggestions are given there for many other configurations. Tested alternative configuration files

You may need to add the package Archive::Zip to your perl installation; the procedure is as for XML::XPath, described at http://code.google.com/p/nmqual/wiki/UserGuide#Installing_NMQual. You
may need to replace "from='../nonmem.lic'" in the configuration file with a full path to your current license.

NMQual is a system for creating NONMEM installations; it features scripted bug fixes and self-documenting output. NMQual is available at http://nmqual.googlecode.com
 

Metrum Institute's ACoP 2009 Workshop

Monday, 05 October 2009 11:00
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UPDATE: The workshop went well. Thanks to all those who attended, and we hope you enjoyed it!

Metrum Institute's Bill Gillespie will be teaching a workshop, Getting Started with Bayesian PK-PD Modeling, at this year's ACoP. The workshop description is as follows:

This introductory course covers the basics of Bayesian modeling theory and the use of WinBUGS for PK-PD applications, including: running WinBUGS from R, nonlinear mixed effects models for PK and PD endpoints, population PK, BQL data, and the new BUGSModelLibrary for PKPD applications.

 

New Course: MI260+

Sunday, 19 July 2009 21:29
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UPDATE: This course has ended. Thanks to all those who participated!

We are pleased to announce a new hands-on, intensive 3-day course (MI260+) scheduled for September 2, 3, and 4, 2009 in Cambridge, MA. This offering will combine an introduction to WinBUGS for pharmacokinetic/pharmacodynamic applications with a detailed overview of Bayesian model-based meta analysis.

Getting Started with Bayesian PK-PD Modeling (Day 1): This introductory course covers the basics of Bayesian modeling theory and the use of WinBUGS for PK-PD applications, including running WinBUGS from R, nonlinear mixed effects models for PK and PD endpoints, population PK, BQL data, and the new BUGSModelLibrary for PKPD applications.

Model-Based Meta-Analysis to Support Decision Making in Clinical Drug Development (Days 2 and 3): MI260 provides an introduction to model-based meta-analysis of summary data or combinations of summary and individual data, and the rationale for applying Bayesian modeling methods to these problems. Hands-on modeling topics, using WinBUGS include dose-response models for landmark and longitudinal summary and individual data, as well as population simulations from meta-analysis models.

Location: Le Meridien Hotel, 20 Sidney Street, Cambridge, MA

Hardware/Software: Participants will be expected to bring their own Windows-based laptop, and software installation instructions will be provided separately. All software tools are freely available or open-source.

Check our training courses page for more information and course outlines. Space is limited, so register soon to make sure you get a spot!

 

New course schedule for 2009-2011

Monday, 15 June 2009 10:35
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Starting this fall, Metrum Institute will set a new 2 year schedule for its courses, which will end with the spring semester of 2011 and then repeat. In addition, some new courses have been added to the schedule, including a new onsite course (MI260) to take place over three days this September. The details of some of these new courses are still being worked out, so check back later for more information.
 
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