Metrum Institute Training Courses

Metrum Institute has expanded its training program for 2008. Many new courses are offered, and some of our most popular courses are restructured. Course outlines are offered below.

Want to view all of our current courses at a glance? Click here for PDF version.

Course # Course Title Dates Location Cost* Outline Registration MI101-W Introduction to Pharmacokinetics and Pharmacodynamics MI101 provides a thorough introduction to fundamental concepts in pharmacokinetics and pharmacodynamics through lectures and problem-solving lab sessions that emphasize physiologic concepts and real-world applications. Content is consistent with expectations for an introductory PK course in a professional pharmacy curriculum. Prerequisites: none Spring 2009--dates TBD webcast $3,000* register online now MI110-W New dates! NMQual for NONMEM® Software Installation & Qualification MI110 demonstrates basic NMQual techniques on a Windows platform, with the aim of executing rapid, well characterized NONMEM® installations. Prerequisites: none Tuesday, Oct. 21, 2008 1-3PM EDT Other dates available--see course outline webcast $200* register online now MI120-W Brief Introduction to R and MItools MI120 is a brief, but intensive hands-on introduction to the R language, with specific focus on functions and features useful in pharmacometrics. This course also includes an introduction to the MItools package, which is used in later courses for processing of NONMEM® runs. Prerequisites: none Spring 2009: Feb. 3 & 6 webcast $300* register online now MI210-W   Essentials of Population PKPD Modeling & Simulation MI210 provides an extensive overview of essential topics in population pharmacokinetics and pharmacodynamics, including: nonlinear-mixed effects modeling theory and implementation, data formatting requirements, population model development, model evaluation techniques, continuous PK-PD models, Monte Carlo simulation, and best practices. Instruction combines didactic lectures with hands-on exercises using R and the NONMEM® software. Prerequisites: Basic understanding of pharmacokinetic and pharmacodynamic principles, compartmental pharmacokinetic models, introductory statistics, familiarity with the R or S language. Applicable MI Courses include: MI120, MI101, MI201, or contact instructor. Fall: Sept. 9-Dec. 12, 2008 webcast $3000* Registration is now closed MI212-W Advanced Topics in Population PK-PD Modeling & Simulation MI212 extends the material inititated in MI210 including a detailed overview of advanced topics in population pharmacokinetics and pharmacodynamics: inter-occasion variability, mixture models, truncated continuous data (BQL), nonlinear-pharmacokinetic models, models for parent & metabolite plasma and urine data, indirect-response pharmacodynamic models, models for tolerance, precursor pools and complex systems, disease progression models, population PK study design, and clinical trial simulation. Instruction combines didactic lectures with hands-on exercises using R and the NONMEM® software. Prerequisites: MI210 and related prerequisites. Spring: Feb. 10 - May 1, 2009 webcast $3000* register online now MI250 Introduction to Bayesian PK-PD Modeling & Simulation MI250 is an intensive, 3-day onsite course that provides an introduction to Bayesian modeling and the practical use of WinBUGS and R for PK-PD applications. Prerequisites: Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is requred. Applicable MI courses include: MI 210 and MI212. July 16-18, 2008 (Wed-Fri) 8:30AM-4:30PM Eastern time The Harborside Bar Harbor, ME Bar Harbor area map w/ airport locations $2475* Registration is closed   MI255 Exposure-Response Modeling of Categorical, Count and Time-to-Event Data Using Bayesian and Maximum Likelihood Methods MI255 provides and introduction to modeling of categorical, count, and time-to-event data, and the practical use of NONMEM® and WinBUGS for such applications. Prequisites: Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is required. Prior experience with Bayesian modeling using WinBUGS is desirable but not required. The course includes a short introduction to Bayesian principles and WinBUGS. Applicable MI courses include: MI210, MI212 and MI250, or contact instructor. July 21-23, 2008 (Mon-Wed) 8:30AM-4:30PM Eastern time The Harborside Bar Harbor, ME Bar Harbor area map w/ airport locations $2475* Registration is closed

*Discounts are offered to academic, non-profit and government agencies. See course outlines for details.
Metrum Institute is continuously developing this curriculum. If you have any suggestions for training topics, please contact us.

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